Null Results Repository

Keywords

Abstract

Cisplatin is a common chemotherapy drug used to treat various types of cancer by damaging cancer cells. It is used in a variety of FDA-approved cancer treatments, in combination with other drugs. We hypothesized that the efficacy of cisplatin could be optimized by finding the optimal concentrations of cisplatin treatment to limit cancer cell proliferation. We treated prostate cancer cells in tissue culture with different concentrations of cisplatin and counted cells every day to measure growth.

Methods

We treated prostate cancer cells in tissue culture with 5 different concentrations of cisplatin and counted cell numbers every day for two weeks.

Expected Outcome

We hypothesized that an intermediate concentration of cisplatin would produce optimal cancer cell death.

Observed Outcome

Results were inconclusive, as all of the concentrations seemed to create the same degree of cell death.